Spitz nevi and atypical Spitz nevi/tumors: a histologic and immunohistochemical analysis

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Hypopigmented atypical Spitzoid neoplasms (atypical Spitz nevi, atypical Spitz tumors, Spitzoid melanoma): a clinicopathological update

The clinicopathologic classification, diagnosis, and management of Spitzoid melanocytic lesions is one of the most problematic topics in dermato-oncology and dermatopathology. After earlier anecdotal reports [1,2], the controversial history of these controversial lesions began in 1948 when Sophie Spitz described 13 cases of what she called “juvenile melanoma,” underlining its presumably good pr...

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Spitz and Reed nevi: acquired or congenital?

Although conflicting with the concept of nevi being hamartomas, to date, Spitz and Reed nevi have been regarded as acquired melanocytic nevi, whereas many other types have already been accepted as being congenital. Here, the reader will find a survey on clinical, dermatoscopic and histopathologic clues suggesting a congenital origin of authentic Spitz nevi. Relevant differences in respect to Re...

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The Spectrum of Spitz Nevi

Main Outcome Measure: Frequency of dermoscopic patterns within the different histopathologic subtypes of Spitz nevi. Results: Overlapping clinical, dermoscopic, and histopathologic findings were observed among PSN, RN, and PSRN, thereby justifying their inclusion into the single PSRN diagnostic category. Asymmetry was the most frequent indicator of histopathologic ASN (79%; n=11); in only 4 cas...

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Osteopontin expression in Spitz nevi.

1. de Waard-van der Spek FB, Mulder PG, Oranje AP. Prilocaine/lidocaine patch as a local premedication for skin biopsy in children. J Am Acad Dermatol. 1997; 37(3, pt 1):418-421. 2. Buckley MM, Benfield P. Eutectic lidocaine/prilocaine cream: a review of the topical anaesthetic/analgesic efficacy of a eutectic mixture of local anaesthetics (EMLA). Drugs. 1993;46(1):126-151. 3. Hoss DM, Gross EG...

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[Agminated Spitz nevi on a hyperpigmented macule].

We present the case of a 2-year-old boy with multiple Spitz nevi clustered on a hyperpigmented macule that obeyed a quadrant distribution. Multiple Spitz nevi are rare and can be disseminated or clustered. A third of the cases of agminated lesions appear on hyperpigmented macules.

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ژورنال

عنوان ژورنال: Modern Pathology

سال: 2004

ISSN: 0893-3952,1530-0285

DOI: 10.1038/modpathol.3800281